• MOLECULAR NEUROPSYCHIATRY LAB
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  • RESEARCH
    Gene Expression
    Cell Signaling
    Structural Biology
    Behavior
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About Us


The Sathyanesan Laboratory focuses on understanding the role played by multifuctional trophic factors in the central nervous system. These molecules, such as erythropoietin (EPO), insulin-like growth factor (IGF), and vascular endothelial growth factor (VEGF), act on multiple cell types in the brain.

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Research


Gene Expression

We have a strong interest in examining gene regulation in several different tissues and cell lines. We employ a combination of high throughput, whole genome investigations, and focused, hypothesis-driven experiments.

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Cell Signaling

We employ neuronal and endothelial cell lines to determine the activation of intracellular signal transduction pathways with high resolution.

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Structural Biology

Our computational structural biology studies are geared towards obtaining deep, atom-level insight of chemically engineered post-translational modifications of trophic factor molecules.

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Behavior

Normal and abnormal animal behavior can be used as a tool to understand the neural substrates of neuropsychiatric disorders.

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